We are keenly interested in infectious diseases, particularly bacterial pathogens. Our current work is on a variety of projects, including tularemia, brucellosis, Q fever, chlamydiosis, anthrax and mycoplasmosis.
A broader understanding of health and disease demands a unity of approach achievable only through a consilience of human, domestic animal and wildlife health. Any disease or infection that is naturally transmissible from vertebrate animals to humans and vice-versa is classified as a zoonosis. Our research projects focus on the following zoonotic bacterial agents: Francisella tularensis, the causative agent of the highly contagious zoonotic disease, tularemia - primarily a disease of the orders Lagomorpha and Rodentia; Brucella species, the causative agent of brucellosis - it manifests in abortion in females and in epididymitis, orchitis and inflammation of accessory genital glands in males of different domestic and wild animal species; Coxiella burnetii, the causative agent of Q fever - occurs worldwide and had been associated mostly with late-term abortion and reproductive disorders in wild and domestic ruminants; Chlamydiales species - causing ornithosis in avian species and abortion in mammals; and Borrelia species, the causative agent of Lyme borreliosis - the most prevalent vector-borne human disease in the temperate zone of the Northern Hemisphere. Our other research field is mycoplasmosis. Mycoplasmas are the smallest self-replicating organisms known. They have a worldwide distribution as free-living saprophytes or as facultative-pathogen parasites of humans, animals and plants. Our research involves the examination of different Mycoplasma species infecting domestic and wild animals.
Sulyok KM, Kreizinger Zs, Wehmann E, Lysnyansky I, Bányai K, Marton Sz, Jerzsele Á, Rónai Zs, Turcsányi I, Makrai L, Jánosi Sz, Nagy SÁ, Gyuranecz M. (2017): Mutations associated with decreased susceptibility to seven antimicrobial families in field and laboratory-derived Mycoplasma bovis strains. Antimicrobial Agents and Chemotherapy, 61(2): e01983-16. doi: 10.1128/AAC.01983-16
Maurin M, Gyuranecz M. (2016): Tularaemia: clinical aspects in Europe. The Lancet Infectious Diseases, 16(1): 113-124. doi: 10.1016/S1473-3099(15)00355-2
Kreizinger Z, Sulyok KM, Pásztor A, Erdélyi K, Felde O, Povazsán J, Kőrösi L, Gyuranecz M (2015): Rapid, simple and cost-effective molecular method to differentiate the temperature sensitive (ts+) MS-H vaccine strain and wild-type Mycoplasma synoviae isolates. PLoS One.10: e0133554. doi: 10.1371/journal.pone.0133554
Gyuranecz M, Sulyok KM, Balla E, Mag T, Balázs A, Simor Z, Dénes B, Hornok S, Bajnóczi P, Hornstra HM, et al. (2014): Q fever epidemic in Hungary. Eurosurveill. 19: 20863. doi: 10.2807/1560-7917.ES2014.19.30.20863
Kreizinger Z, Foster JT, Rónai Z, Sulyok KM, Wehmann E, Jánosi S, Gyuranecz M (2014): Genetic relatedness of Brucella suis biovar 2 isolates from hares, wild boars and domestic pigs. Vet Microbiol. 172:492-498. doi: 10.1016/j.vetmic.2014.05.031
Kreizinger Z, Makrai L, Helyes G, Magyar T, Erdélyi K, Gyuranecz M (2013): Antimicrobial susceptibility of Francisella tularensis subsp. holarctica isolates from Hungary, Central Europe. J Antimicrob Chemother. 68:370-373. doi: 10.1093/jac/dks399