Fluoroquinolones are drugs of prime importance, however the number of resistant bacteria is increasing worldwide. Plasmid-mediated resistance determinants confer low level resistance, which can lead to therapy failure. Better understanding the mechanism of PMQR may help to prevent resistance against fluoroquinolones.
Szabó, Dóra (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
OTKA K 108481