Respiratory Bacteriology Research Team

Scientific advisor, director of the Institute, research team leader: 
The team studies virulence factors and signs of host adaptation of Bordetella bronchiseptica, a pathogen causing a wide variety of disease in multiple animal hosts (atrophic rhinitis in swine, kennel cough in dogs, bronchopneumonia in cats and rabbits, and sporadic cases in humans) by traditional microbiological and molecular genetic (PCR, PCR-RFLP, sequence and phylogenetic analysis) methods.
 
Diseases caused by Pasteurella multocida (atrophic rhinitis in swine, haemorrhagic septicaemia in cattle, fowl cholera in poultry, pneumonia in various species, and pasteurellosis in rabbits) result in considerable economic losses for animal husbandry. Traditional (biochemical tests, serotyping, antimicrobial resistance testing) and molecular genetic (PCR, sequence and phylogenetic analysis) methods are applied to analyse P. multocida strains from various animal hosts in order to identify virulence factors and learn more about the pathogenesis of these diseases.
 
We also examine the prevalence of Bordetella avium, Ornithobacterium rhinotracheale and Riemerella anatipestifer in wild birds and commercial poultry farms. Isolates are characterised by analysing their phenotypic properties, genotyping and determination of antimicrobial susceptibility.
 
We offer services to perform laboratory and field trials to test veterinary medicines and vaccines in order to develop modern and more effective preventative methods against infectious diseases of veterinary importance.
Main activities of the Respiratory Bacteriology Research Team.

Main activities of the Respiratory Bacteriology Research Team.

Services: 

Characterisation of various bacterial respiratory pathogens by traditional and molecular genetic diagnostic methods (e. g. slide agglutination, ELISA, PCR); animal experiments for vaccination studies.

Selected publications: 

Ujvári B, Szeredi L, Pertl L, Tóth G, Erdélyi K, Jánosi S, Molnár T, Magyar T (2015): First detection of Pasteurella multocida type B:2 in Hungary associated with systemic pasteurellosis in backyard pigs. Acta Vet Hung. 63(2): 141-156. doi: 10.1556/AVet.2015.012

Szabó R, Wehmann E, Magyar T (2015): Antimicrobial susceptibility of Bordetella avium and Ornithobacterium rhinotracheale strains from wild and domesticated birds in Hungary. Acta Vet Hung. 63(4):413-424. doi: 10.1556/004.2015.039.

Wehmann E, Khayer B, Magyar T (2015): Heterogeneity of Bordetella bronchiseptica adenylate cyclase (cyaA) RTX domain. Arch Microbiol. 197(1): 105-112. doi: 10.1007/s00203-014-1068-x

Khayer B, Magyar T, Wehmann E (2014): Flagellin typing of Bordetella bronchiseptica strains originating from different host species. Vet Microbiol. 173(3-4): 270-278. doi: 10.1016/j.vetmic.2014.07.016

Pósa R, Stoev S, Kovács M, Donkó T, Repa I, Magyar T (2014): A comparative pathological finding in pigs exposed to fumonisin B1 and/or Mycoplasma hyopneumoniae. Toxicol Ind Health, Paper 0748233714543735, doi: 10.1177/0748233714543735

Magyar T, Donkó T, Repa I, Kovács M (2013) Regeneration of toxigenic Pasteurella multocida induced severe turbinate atrophy in pigs detected by computed tomography. BMC Vet Res. 9: 222. doi: 10.1186/1746-6148-9-222

Pósa R, Magyar T, Stoev S, Glávits R, Donkó T, Repa I, Kovács M (2013) Use of computed tomography and histopathologic review for lung lesions produced by the interaction between Mycoplasma hyopneumoniae and fumonisin mycotoxins in pigs. Vet Pathol. 50(6): 971-979. doi: 10.1177/0300985813480510

Sellyei B, Wehmann E, Magyar T (2012) Sequencing-independent method for the differentiation of the main phylogenetic lineages of Pasteurella multocida. J Vet Diagn Invest. 24(4): 735-738. doi: 10.1177/1040638712447794

Khayer B, Rónai ZS, Wehmann E, Magyar T (2011) Detection of urease-negative Bordetella bronchiseptica from the field. Acta Vet Hung. 39(3): 289-293. doi: 10.1556/AVet.2011.025

Pósa R, Donkó T, Bogner P, Kovács M, Repa I, Magyar T (2011) Interaction of Bordetella bronchisepticaPasteurella multocida, and fumonisin B1 inthe porcine respiratory tract as studied by computed tomography. Can J Vet Res. 75(3): 176-182.

National and international cooperations: 
Kaposvár University, Kaposvár, Hungary
CEVA-Phylaxia, Budapest, Hungary
CEVA, Libourne, France
MERIAL, Lyon, France;
Boehringer Ingelheim Vetmedica GmbH, Ingelheim, Germany
Senior research fellow(s): 
Assistant research fellow(s):